| Date | Topic | Speaker |
| September 19, 2024 | Reviewing the literature | Rich Haspel |
| October 17, 2024 | Qualitative vs. quantitative research | Tori Lenet |
| November 21, 2024 | Explanatory vs pragmatic trials | (Cancelled) |
| December 19, 2024 | Quasi-experimental trial design | Monica Taljaard |
| January 16, 2025 | Adaptive and platform trials | Ryan Zarychanski |
| February 20, 2025 | Statistical considerations | Robert Balshaw |
| March 20, 2025 | Assembling the research team | Rena Buckstein |
| April 17, 2025 | Retaining the patient perspective | Jennie Haw |
| May 15, 2025 | Sourcing funding | Keyvan Karkouti |
| June 19, 2025 | Piloting the protocol | Shane English |
| July 17, 2025 | Conducting the trial | Nadine Shehata |
| August 21, 2025 | Publishing the results | Paul Hebert |